Chiefs vs 49ers Predictions, Prop Bets October 23

Submitted by Tyrone Black on

Written by :

Tyrone Black

Published on :

Chiefs vs 49ers Predictions, Prop Bets

The Kansas City Chiefs are coming off a close loss to the Buffalo Bills. The San Francisco 49ers suffered a tough loss in Atlanta and will be happy to be back home. When 2 Super Bowl contenders meet up, should you look to the side or the total to find the winning NFL pick?

2-footballisback-300x250.gif

The line on this game was coming in at Chiefs -2.5 after being as high as -3.  A few books had moved to -2 on Friday.  The news of the Christian McCaffrey trade to the 49ers appears to have had little impact on this week's game line, at least so far.

The trend for favorites of -2.5 covering in 10 out of 11 games had cooled off last week. 

We get a number of 2.36, indicating an accurate betting line here. 

A comparable game would be Baltimore -2.5/-3 vs. New England whereby the road favorite Baltimore covered with a 11 point win.  The line on this one was on the money as well. 

BetUS host TJ Rives, and expert handicappers Scot Kellen and Chris Farley analyze the NFL game Kansas City Chiefs vs San Francisco 49ers. They'll go over the latest football betting trends, and best value NFL odds available and share their football picks and expert predictions for this NFL Week 7 game.

Chiefs vs. 49ers Prop Bets

Rot     Player to Score First Touchdown in The Game     Moneyline
101     Travis Kelce (KC)         +650
102     Clyde Edwards-Helaire (KC)         +700
103     Jerick McKinnon (KC)         +1100
104     Juju Smith-Schuster (KC)         +1200
105     Marquez Valdes-Scantling (KC)         +1600
106     Isiah Pacheco (KC)         +1800
107     Patrick Mahomes (KC)         +2000
108     Mecole Hardman (KC)         +2200
109     Jody Fortson (KC)         +2800
110     Justin Watson (KC)         +3300
111     Noah Gray (KC)         +4000
112     Skyy Moore (KC)         +4000
113     Deebo Samuel (SF)         +700
114     Jeff Wilson (SF)         +750
115     Brandon Aiyuk (SF)         +1200
116     George Kittle (SF)         +1200
117     Tevin Coleman (SF)         +1600
118     Jauan Jennings (SF)         +2000
119     Kyle Juszczyk (SF)         +3300
120     Ross Dwelley (SF)         +3300
121     Charlie Woerner (SF)         +5000
122     Jimmy Garoppolo (SF)         +5000
123     Tyrion Davis-Price (SF)         +5000
124     Ray-Ray McCloud (SF)         +6600
125     Any Other Touchdown Scorer         +700
126     No Touchdown Scorer         +10000
Rot     Patrick Mahomes (KC) Total Passing Yards     Moneyline
1001     Over  290½  Passing Yards     Ev
1002     Under  290½  Passing Yards     -130
Must Start for action.
Rot     Patrick Mahomes (KC) Total Touchdown Passes     Moneyline
1007     Over  2½  TD Passes     +150
1008     Under  2½  TD Passes     -180
Must Start for action.
Rot     Patrick Mahomes (KC) Total Interceptions     Moneyline
1011     Over  ½  Interceptions     -105
1012     Under  ½  Interceptions     -125
Rot     Clyde Edwards-Helaire (KC) Total Rushing Attempts     Moneyline
1043     Over  9½  Rush Attempts     -115
1044     Under  9½  Rush Attempts     -115
Must Play for action. Must have 1 Rush Attempt for Action.
Rot     Clyde Edwards-Helaire (KC) Longest Rush From Scrimmage     Moneyline
1047     Over  10½  Yards     -115
1048     Under  10½  Yards     -115
Must Play for action. Must have 1 Rush Attempt for Action.
Rot     Clyde Edwards-Helaire (KC) Total Receptions     Moneyline
1049     Over  2½  Receptions     Ev
1050     Under  2½  Receptions     -130
Rot     Winning Margin     Moneyline
3089     Chiefs to win by 1-6 pts         +300
3090     Chiefs to win by 7-12 pts         +500
3091     Chiefs to win by 13-18 pts         +700
3092     Chiefs to win by 19-24 pts         +1200
3093     Chiefs to win by 25-30 pts         +2200
3094     Chiefs to win by 31-36 pts         +3500
3095     Chiefs to win by 37-42 pts         +5000
3096     Chiefs to win by 43 or More pts         +7500
3097     49ers to win by 1-6 pts         +330
3098     49ers to win by 7-12 pts         +600
3099     49ers to win by 13-18 pts         +900
3100     49ers to win by 19-24 pts         +1800
3101     49ers to win by 25-30 pts         +3300
3102     49ers to win by 31-36 pts         +4500
3103     49ers to win by 37-42 pts         +7500
3104     49ers to win by 43 or More pts         +10000
3105     Tie         +5000

- Tyrone Black, Gambling911.com

Related Content

Gambling911.com news 24/7

Live Gambling News, Top Trending: Updates 24/7 - Friday April 17, 2026

Live News: - Dave & Busters Lawsuit - Damon Jones - Kentucky Derby - Senate Odds
Top gambling news

Live Gambling News, Top Trending: Updates 24/7 - Thursday April 16, 2026

Live News: - Dave & Busters Lawsuit - Damon Jones - Pete Hegseth Impeachment - ECJ German Gambling Ruling - Indonesia Online Gambling Crackdown
Handcuffs

Massachusetts Man Charged in Gambling-Linked Dog Fighting Ring: 'I Dump Dead Dogs in Boston Harbor'

Corey Elliott ran gambling-linked dog fighting operation in Southeastern Massachusetts for years, according to the complaint.
Wtestlemania 42 Vegas

WrestleMania 42 Prop Bets

The oddsmakers at BetOnline.ag have created 25 props to accompany the 13 match lines.